Regenerative Aesthetics · Rejuran · Dubai & Abu Dhabi

Rejuran Treatment in Dubai

Rejuran is a PDRN-based injectable skin healer derived from salmon DNA that repairs damaged skin cells, stimulates collagen production, and restores skin quality from within. Dr Azra Vaziri uses Rejuran Healer as part of her regenerative aesthetics protocols for patients seeking deep biological skin repair.

Rejuran PDRN skin healer treatment in Dubai by Dr Azra Vaziri

Procedure Time
30–45 minutes
Recovery
Bumps 24–48 hours
Sessions
3–4 recommended
Results
Build over 4–6 weeks

What Is Rejuran

Rejuran — also known as Rejuran Healer or the “baby salmon injection” — is a PDRN-based injectable treatment originally developed in South Korea. PDRN (polydeoxyribonucleotide) is a bioactive molecule extracted from salmon DNA that activates your skin’s own repair mechanisms at a cellular level.

In Simple Terms

Rejuran is a skin healer, not a filler or booster. It works by injecting PDRN (salmon DNA fragments) into the skin to activate cellular repair, reduce inflammation, and stimulate collagen from within. It treats dull skin, fine lines, scars, enlarged pores, and dark circles. Treatment takes 30–45 minutes, requires 3–4 sessions, and results build progressively over weeks.

Unlike skin boosters that hydrate or Profhilo that bio-remodels, Rejuran works through the DNA salvage pathway — providing nucleotides that damaged cells need to repair themselves. It also binds to adenosine A2A receptors, producing a powerful anti-inflammatory effect. The result is skin that heals itself from within rather than being temporarily plumped or filled.

Rejuran sits within Dr Azra’s broader polynucleotide and regenerative aesthetics offering. For a detailed comparison with other regenerative treatments, read what are polynucleotides and our salmon DNA facial guide.

What Rejuran Treats
  • Dull, dehydrated, tired-looking skin
  • Fine lines and early wrinkles
  • Acne scarring and enlarged pores
  • Dark circles and under-eye hollowing
  • Uneven skin tone and texture
Treatment Highlights
  • Biologically active — repairs at cellular level
  • Anti-inflammatory (adenosine A2A pathway)
  • 30–45 minute procedure
  • Minimal downtime — bumps resolve in 24–48 hours
  • Results build progressively over 4–6 weeks

Rejuran Product Range

Rejuran comes in several formulations, each designed for specific skin concerns and treatment areas.

Most Popular

Rejuran Healer

The original PDRN skin healer. Targets overall skin quality — texture, tone, hydration, and fine lines. Best for full-face rejuvenation and general skin repair. The foundation of most Rejuran protocols.

Under-Eye Specialist

Rejuran I (Eye)

Specifically formulated for the delicate periorbital area. Treats dark circles, under-eye crepiness, and fine lines around the eyes. Lower viscosity for safe use in thin-skinned areas.

Hydration Boost

Rejuran HB

Combines PDRN with hyaluronic acid for patients who need both biological repair and immediate hydration. Best for severely dehydrated skin that needs structural healing alongside moisture restoration.

How Rejuran Treatment Works

1

Consultation

Skin assessment, concern discussion, and Rejuran product selection with Dr Azra.

2

Numbing

Topical anaesthetic cream applied for 20 minutes to ensure comfort during injection.

3

PDRN Injection

Micro-injections of Rejuran across the treatment area. 30–45 minutes. Can be delivered via needle or Dermapen.

4

Heal & Repair

Small bumps resolve 24–48 hours. PDRN activates repair over 4–6 weeks. Repeat every 2–4 weeks.

Rejuran vs Other Skin Treatments

TreatmentMechanismBest ForSessions
Rejuran (PDRN)DNA repair + anti-inflammationSkin repair, scars, dark circles3–4
ProfhiloHA bio-remodellingSkin laxity, hydration, fine lines2
Skin BoostersHA micro-injection hydrationDehydration, glow, superficial lines3
ExosomesCell-derived signalling vesiclesDeep regeneration, post-procedure3–4
PRPAutologous growth factorsNatural regeneration, hair, healing3–4

See also: Profhilo vs Rejuran · Profhilo vs polynucleotides · PRP vs exosomes

Who Is a Good Candidate for Rejuran

Ideal Candidates
  • Dull, tired-looking skin needing repair
  • Fine lines and early signs of ageing
  • Acne scarring or post-inflammatory marks
  • Dark circles and under-eye ageing
  • Sun-damaged or heat-stressed skin (common in Dubai)
  • Patients wanting biological repair, not just hydration
Considerations
  • Allergy to fish or salmon products
  • Pregnancy or breastfeeding
  • Active skin infection in treatment area
  • Keloid scarring tendency
  • Autoimmune conditions (discuss with Dr Azra)

Consultation with Dr Azra determines suitability and selects the right Rejuran formulation.

Rejuran Care Guidelines

Before Treatment
  • Avoid blood thinners for 1 week
  • Avoid alcohol for 48 hours
  • Inform Dr Azra of any fish allergies
  • Stay hydrated
  • Arrive with clean skin — no makeup
After Treatment
  • Small bumps at injection sites — resolve in 24–48 hours
  • No makeup for 12 hours
  • Avoid sun exposure and heat for 48 hours
  • No active skincare (retinol, AHA) for 48 hours
  • Use gentle cleanser and SPF from day 2
  • Results build over 4–6 weeks per session

Related Treatments

PolynucleotidesDNA-based skin repair

Salmon DNAPDRN skin treatment

ProfhiloHA bio-remodelling

Exosome TherapyCellular regeneration

View all regenerative treatments →

Related Articles

What Is PDRN?Understanding the science behind Rejuran

Profhilo vs RejuranBio-remodelling vs DNA repair

Salmon DNA Facial ExplainedHow PDRN treatments work

Frequently Asked Questions

What is Rejuran?

Rejuran is a PDRN-based injectable skin healer derived from salmon DNA. It activates cellular repair pathways, stimulates collagen and elastin production, reduces inflammation, and improves skin hydration, elasticity, and texture. It is one of the most popular regenerative skin treatments globally and is now widely available in Dubai.

Profhilo is a hyaluronic acid bio-remodeller that hydrates and tightens skin. Rejuran is a PDRN that repairs skin at the DNA level. Profhilo works from the outside in (hydration → collagen). Rejuran works from the inside out (cellular repair → regeneration). They complement each other and can be combined. Read our Profhilo vs Rejuran comparison.

Rejuran is a branded PDRN product — a specific type of polynucleotide. All PDRN is polynucleotide-based, but not all polynucleotide products are Rejuran. Rejuran Healer uses a specific molecular weight and concentration optimised for skin repair. Other brands include Plinest, Nucleofill, and Mastelli.

Most patients need 3–4 sessions spaced 2–4 weeks apart. Improvement is progressive — skin quality continues to improve for several weeks after each session. Maintenance sessions every 3–6 months sustain results.

Rejuran is derived from salmon DNA — specifically the PDRN extracted from salmon. “Salmon DNA treatment” is a general term encompassing Rejuran and similar PDRN products. Rejuran Healer is the most recognised branded version. See our salmon DNA facial guide.

Small raised bumps at injection sites are normal and resolve within 24–48 hours. Mild redness may last a day. Most patients return to normal activities immediately. Avoid makeup for 12 hours, sun exposure for 48 hours, and active skincare for 2–3 days.

Yes. Dr Azra commonly combines Rejuran with Profhilo for hydration + repair, Dermapen microneedling for enhanced penetration, or skin boosters for combined hydration and biological repair. The best combination is determined during consultation.

Book A Consultation With Dr Azra

Patients seeking personalized aesthetic assessment in Dubai or Abu Dhabi can contact Dr Azra for consultation regarding PRP, exosome therapy, and regenerative skin treatment planning.

Dr Azra Vaziri is a DHA and DOH licensed aesthetic physician practicing in Dubai and Abu Dhabi, with over 20 years of experience in aesthetic medicine, injectables, thread lifting, and non-surgical facial rejuvenation.