Aliaxin is a range of hyaluronic acid fillers manufactured by IBSA Derma, a Swiss pharmaceutical company specialising in hyaluronic acid research. Aliaxin products are CE-marked and used across Europe, the Middle East, and Asia.

What makes Aliaxin unique is its patented NAHYCO (Natural Hyaluronic Acid Hybrid Cooperative) technology. Unlike conventional fillers that only fill, NAHYCO combines high molecular weight HA (for volume and structure) with low molecular weight HA (for biostimulation) through thermal bonding — without chemical cross-linkers. This means Aliaxin provides immediate volumising plus ongoing stimulation of collagen and elastin production, addressing collagen loss and early signs of aging at a deeper level.

This dual-action approach positions Aliaxin between traditional dermal fillers and biostimulators — providing the instant gratification of filler with longer-term skin quality improvement similar to regenerative aesthetic protocols. Dr Azra Vaziri particularly values Aliaxin Shape for jawline and chin contouring, and Aliaxin EV for patients seeking non-surgical facial rejuvenation.

Aliaxin Shape

Firm, high-projection filler for structural contouring. Excellent definition along bone with a natural feel. Dr Azra’s top choice for jawline and chin sculpting, and for patients considering a non-surgical facelift approach.

Duration: 12–18 months

Aliaxin Essential

Medium-density filler for moderate lines and soft volume. Smooth, natural-feeling results in areas requiring subtlety. Effective for fine lines and early fold correction.

Duration: 8–12 months

Aliaxin EV

Extra Volume with biostimulatory effect. Deep volume restoration combined with collagen stimulation for lasting improvement in skin quality. Particularly effective for patients experiencing post-weight-loss volume depletion or age-related mid-face hollowing.

Duration: 12–18 months (biostimulation ongoing)

Aliaxin SR

Skin Rejuvenation booster. NAHYCO technology focused on improving skin quality, hydration, and elasticity through biostimulation. Similar in concept to skin boosters and Profhilo but with Aliaxin’s hybrid HA approach.

Protocol: 2–3 sessions, 3–4 weeks apart

Most fillers use chemical cross-linking agents (like BDDE) to stabilise hyaluronic acid gel. NAHYCO takes a different approach — it bonds high and low molecular weight HA through a thermal (heat-based) process, creating a hybrid cooperative complex without chemical cross-linkers.

The result is a dual-action product: the high molecular weight HA provides immediate volume and structure, while the low molecular weight HA stimulates fibroblasts to produce new collagen and elastin — a mechanism shared with collagen stimulation treatments and polynucleotide therapy. This means the treatment continues improving skin quality even as the filler gradually metabolises. Learn more about how regenerative skin treatments work.

• Volume restoration and contouring
• Structural projection along bone
• Line and fold softening
• Visible results from day one

• Collagen and elastin stimulation
• Improved skin quality over weeks
• Benefits extend beyond filler duration
• Complementary to biostimulators

Dr Azra frequently combines Aliaxin with complementary treatments for comprehensive facial rejuvenation. Aliaxin Shape for jawline definition pairs well with Botox for masseter slimming or forehead smoothing. For patients with skin laxity, Aliaxin volumising combined with thread lifting provides both structural support and tissue repositioning.

Aliaxin SR can also be layered alongside skin treatments such as skin boosters or PRP for patients whose concerns span both volume loss and overall skin quality decline. Patients dealing with dark circles or tear trough hollowing may benefit from Aliaxin EV combined with polynucleotide therapy for periorbital rejuvenation.