PDRN Skin Booster · Dubai & Abu Dhabi
TwAc in Dubai — the PDRN Booster That Comes With Hyaluronic Acid
TwAc is a PDRN skin booster — purified salmon-DNA polynucleotides combined with hyaluronic acid, injected to repair skin quality rather than add volume. Given by Dr Azra Vaziri in Dubai and Abu Dhabi.
✓ PDRN + hyaluronic acid in one booster
✓ Repairs skin quality, adds no volume
✓ Face, under-eyes, neck and hands
✓ AED 1,300, currently AED 1,100
Looking for the Taiwan Arrival Card? That is a different TWAC entirely — this page is about the injectable skin booster.
What is TwAc? TwAc — Transdermal Wound Activation Complex — is an injectable skin booster that combines PDRN (polydeoxyribonucleotide, purified from salmon DNA) with hyaluronic acid. The PDRN signals fibroblasts to repair and rebuild; the hyaluronic acid hydrates at the same time. It treats skin quality — texture, tone, fine lines, dull or tired skin, under-eye shadowing — and adds no volume, so it is not a filler. At Dr Azra Vaziri’s clinic it is AED 1,300, currently AED 1,100, usually as a short course.
If you came here for the wider topic: what PDRN actually is · polynucleotide treatment · Rejuran · skin booster prices
⎯ The Product
What Is TwAc?
TwAc is a bioreparant skin booster: PDRN from purified salmon DNA, formulated together with hyaluronic acid. It is injected into the skin to repair quality, not underneath it to create shape.
PDRN — polydeoxyribonucleotide — is made of short, purified DNA fragments. Injected into the dermis it activates fibroblasts, improves microcirculation and damps inflammation, so the skin behaves more like younger skin rather than being padded out to look like it.
What separates TwAc from a pure PDRN product is the second ingredient. Rejuran, the best-known salmon-DNA booster, is PDRN on its own: the repair signal without a hydrating carrier. TwAc pairs the same class of molecule with hyaluronic acid, so hydration and glow arrive within days while the regenerative work happens quietly over the following weeks.
It is sold as a small family — TwAc Eyes for the under-eye area, TwAc 2.0 for early ageing and hydration, and TwAc 3.0 for more mature skin, the neck and the hands. Which one suits you is decided at the consultation, not ordered from a menu.
⎯ How It Works
Repair, Not Fill
A filler occupies space. A booster changes the tissue. TwAc is firmly in the second category, and the mechanism is worth understanding because it explains why nothing dramatic happens on the day and why the result keeps improving after you have stopped thinking about it.
The PDRN fragments act as signalling molecules: they bind receptors on fibroblasts and switch them toward repair — new collagen and elastin, better microcirculation, less oxidative stress. The hyaluronic acid does something simpler and faster: it holds water, so the skin looks plumper and brighter within days while the slower work is still under way.
That split is also why TwAc is given as a course rather than a single session. One injection gives a signal; three, spaced two to four weeks apart, give a sustained one.
TwAc Treatment Areas
Anywhere the complaint is skin quality rather than shape.
| Area | What it is used for | Which formulation |
|---|---|---|
| Face | Dull, tired skin, uneven texture, fine lines, early laxity | TwAc 2.0 or 3.0 |
| Under-eyes | Shadowing, crepiness and fine lines — not hollowing | TwAc Eyes |
| Neck | Crepey texture and horizontal lines | TwAc 3.0 |
| Décolletage | Sun damage, texture, fine crinkling | TwAc 3.0 |
| Hands | Thin, crepey skin on the back of the hand | TwAc 3.0 |
The formulation is chosen at the consultation. Under-eye HOLLOWING is a volume problem and needs a different treatment — see tear-trough filler.
TwAc, Rejuran, Polynucleotides and Profhilo
These overlap, and the honest answer is that the differences between them matter less than whether a booster is the right category for you at all. Dr Azra picks on your skin, not on the brand.
| TwAc | Rejuran | Polynucleotides (generic) | Profhilo | |
|---|---|---|---|---|
| Active | PDRN + hyaluronic acid | PDRN (salmon DNA) | PN / PDRN, various brands | High-concentration HA |
| Main job | Repair + hydration | Repair | Repair | Hydration and bio-remodelling |
| Adds volume | No | No | No | No |
| Typical course | 3 sessions | 3–4 sessions | 3 sessions | 2 sessions |
| Price / session | AED 1,100 | AED 1,500 | from AED 1,100 | AED 1,300 |
Prices are the current after-discount rates from Dr Azra’s list and are “from” figures; the plan is confirmed in clinic.
Full explanations: Rejuran · polynucleotide treatment · Profhilo vs Rejuran · what PDRN is.
⎯ The Session
What the Appointment Is Like
Numbing cream first, then a series of small injections across the treatment area. It takes twenty to thirty minutes. You will have small raised bumps where the product was placed — these settle within a few hours, occasionally overnight.
Most people go straight back to work. Leave make-up off for the rest of the day, skip the gym and anything hot for forty-eight hours, and no facials or actives for a week. The full care guidance is on the salmon DNA aftercare page, which covers PDRN boosters as a family.
TwAc Price in Dubai
TwAc at Dr Azra’s clinic is AED 1,300 per session, currently AED 1,100 after discount. Boosters work as a course, so the figure worth planning around is three sessions — and whether you need three is decided after your skin is assessed, not before.
| Per session | Typical course of 3 | |
|---|---|---|
| TwAc | AED 1,100 | AED 3,300 |
From Dr Azra’s current clinic list. Sessions are spaced two to four weeks apart. See the full clinic price list or the skin booster price guide to compare across the family.
⎯ Safety
Side Effects and Who Should Not Have It
Polynucleotide boosters are among the better-tolerated injectables. The usual effects are the injection ones: small bumps for a few hours, redness, occasional pinpoint bruising. They settle without treatment.
TwAc is derived from salmon DNA, so it is not suitable if you have a fish allergy — say so at the consultation. It is also avoided in pregnancy and breastfeeding, with active infection or inflammation in the treatment area, and during an autoimmune flare, which is discussed case by case.
One honest limitation: a booster improves skin, it does not lift it. If what troubles you is sagging rather than surface quality, a thread lift or a biostimulator is the truthful answer, and you will get it.
TwAc FAQ
Related Treatments
TwAc is one product in a family we treat with every week. These pages explain the rest.
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Dr Azra Vaziri — DHA & DOH licensed aesthetic physician with 20+ years of experience, practising in Dubai and Abu Dhabi.


