PDRN Skin Booster · Dubai & Abu Dhabi
TwAc in Dubai — the PDRN Booster That Comes With Hyaluronic Acid
TwAc is a PDRN skin booster — purified salmon-DNA polynucleotides combined with hyaluronic acid, injected to repair skin quality rather than add volume. Given by Dr Azra Vaziri in Dubai and Abu Dhabi.
On this page: What TwAc Is
- 20+Years' experience
- DHA · DOHLicensed
- 2Clinics
- 5.0Google rating
- What it is
- PDRN booster with HA
- TwAc stands for
- Transdermal Wound Activation Complex
- Source
- Purified salmon DNA
- Adds volume?
- No — it is not a filler
- Course
- Usually 3 sessions, 2–4 weeks apart
- Price
- AED 1,300 → AED 1,100
TwAc in Dubai — the PDRN Booster That Comes With Hyaluronic Acid at a glance
TwAc in Dubai - the PDRN skin booster that pairs purified salmon-DNA polynucleotides with hyaluronic acid to repair skin quality. From AED 1,100 with Dr Azra Vaziri.
- What it is
- PDRN booster with HA
- TwAc stands for
- Transdermal Wound Activation Complex
- Source
- Purified salmon DNA
- Adds volume?
- No — it is not a filler
- Course
- Usually 3 sessions, 2–4 weeks apart
- Price
- AED 1,300 → AED 1,100
- PDRN + hyaluronic acid in one booster
✓ Repairs skin quality, adds no volume
✓ Face, under-eyes, neck and hands
✓ AED 1,300, currently AED 1,100
Performed by Dr Azra Vaziri at Prof Sakla Spanish Eye Clinic, Dubai
⎯ The Product
What Is TwAc?
TwAc is a bioreparant skin booster: PDRN from purified salmon DNA, formulated together with hyaluronic acid. It is injected into the skin to repair quality, not underneath it to create shape.
PDRN — polydeoxyribonucleotide — is made of short, purified DNA fragments. Injected into the dermis it activates fibroblasts, improves microcirculation and damps inflammation, so the skin behaves more like younger skin rather than being padded out to look like it.
What separates TwAc from a pure PDRN product is the second ingredient. Rejuran, the best-known salmon-DNA booster, is PDRN on its own: the repair signal without a hydrating carrier. TwAc pairs the same class of molecule with hyaluronic acid, so hydration and glow arrive within days while the regenerative work happens quietly over the following weeks.
It is sold as a small family — TwAc Eyes for the under-eye area, TwAc 2.0 for early ageing and hydration, and TwAc 3.0 for more mature skin, the neck and the hands. Which one suits you is decided at the consultation, not ordered from a menu.
TwAc is not a filler and it is not Botox. It will not restore a flattened cheek or sharpen a jawline — for that you want filler or a biostimulator. TwAc changes how the skin itself looks and behaves. The two jobs are often done together, in different sessions.
PDRN + HA Together
The repair signal and the hydration in one injection — the thing that distinguishes TwAc from PDRN-only boosters
Salmon DNA Origin
Highly purified polynucleotides from salmon DNA, the same family as the salmon DNA facial people ask for by name
Skin Quality, Not Volume
Texture, tone, fine lines, dullness, under-eye shadowing and early laxity — nothing is filled
Three Formulations
TwAc Eyes for the under-eye, TwAc 2.0 for early ageing, TwAc 3.0 for mature skin, neck and hands
TwAc — Key Facts at a Glance
Full name
Transdermal Wound Activation Complex
Active
PDRN / polynucleotides from purified salmon DNA
Second ingredient
Hyaluronic acid
How many sessions your skin needs is decided after an assessment — book a consultation.
⎯ How It Works
Repair, Not Fill
A filler occupies space. A booster changes the tissue. TwAc is firmly in the second category, and the mechanism is worth understanding because it explains why nothing dramatic happens on the day and why the result keeps improving after you have stopped thinking about it.
The PDRN fragments act as signalling molecules: they bind receptors on fibroblasts and switch them toward repair — new collagen and elastin, better microcirculation, less oxidative stress. The hyaluronic acid does something simpler and faster: it holds water, so the skin looks plumper and brighter within days while the slower work is still under way.
That split is also why TwAc is given as a course rather than a single session. One injection gives a signal; three, spaced two to four weeks apart, give a sustained one.
Hydration, within days
The hyaluronic acid component holds water in the dermis. Skin looks fresher and brighter first — this is the part patients notice in the first week.
Repair signal, weeks 2–6
PDRN activates fibroblasts toward collagen and elastin production, improves microcirculation and reduces inflammation in the treated skin.
Quality change, weeks 4–8
Texture evens out, fine lines soften, tone improves. This is the result the course was for, and it arrives gradually rather than overnight.
⎯ Where It Is Used
TwAc Treatment Areas
Anywhere the complaint is skin quality rather than shape.
The formulation is chosen at the consultation. Under-eye HOLLOWING is a volume problem and needs a different treatment — see tear-trough filler.
| Area | What it is used for | Which formulation |
|---|---|---|
| Face | Dull, tired skin, uneven texture, fine lines, early laxity | TwAc 2.0 or 3.0 |
| Under-eyes | Shadowing, crepiness and fine lines — not hollowing | TwAc Eyes |
| Neck | Crepey texture and horizontal lines | TwAc 3.0 |
| Décolletage | Sun damage, texture, fine crinkling | TwAc 3.0 |
| Hands | Thin, crepey skin on the back of the hand | TwAc 3.0 |
⎯ Where TwAc Sits
TwAc, Rejuran, Polynucleotides and Profhilo
These overlap, and the honest answer is that the differences between them matter less than whether a booster is the right category for you at all. Dr Azra picks on your skin, not on the brand.
Prices are the current after-discount rates from Dr Azra’s list and are “from” figures; the plan is confirmed in clinic.
Full explanations: Rejuran · polynucleotide treatment · Profhilo vs Rejuran · what PDRN is.
| TwAc | Rejuran | Polynucleotides (generic) | Profhilo | |
|---|---|---|---|---|
| Active | PDRN + hyaluronic acid | PDRN (salmon DNA) | PN / PDRN, various brands | High-concentration HA |
| Main job | Repair + hydration | Repair | Repair | Hydration and bio-remodelling |
| Adds volume | No | No | No | No |
| Typical course | 3 sessions | 3–4 sessions | 3 sessions | 2 sessions |
| Price / session | AED 1,100 | AED 1,500 | from AED 1,100 | AED 1,300 |
⎯ The Session
What the Appointment Is Like
Numbing cream first, then a series of small injections across the treatment area. It takes twenty to thirty minutes. You will have small raised bumps where the product was placed — these settle within a few hours, occasionally overnight.
Most people go straight back to work. Leave make-up off for the rest of the day, skip the gym and anything hot for forty-eight hours, and no facials or actives for a week. The full care guidance is on the salmon DNA aftercare page, which covers PDRN boosters as a family.
TwAc suits you if…
Your complaint is skin quality — dull, tired, crepey, uneven texture, fine lines, under-eye shadowing — and you want repair rather than volume. It combines well with Botox and with filler done separately.
Something else suits you better if…
You have lost volume and want shape restored, or your under-eye problem is a hollow rather than a shadow, or you are hoping one session will change your face. Boosters reward a course and patience.
⎯ Cost
TwAc Price in Dubai
TwAc at Dr Azra’s clinic is AED 1,300 per session, currently AED 1,100 after discount. Boosters work as a course, so the figure worth planning around is three sessions — and whether you need three is decided after your skin is assessed, not before.
From Dr Azra’s current clinic list. Sessions are spaced two to four weeks apart. See the full clinic price list or the skin booster price guide to compare across the family.
| Per session | Typical course of 3 | |
|---|---|---|
| TwAc | AED 1,100 | AED 3,300 |
⎯ Safety
Side Effects and Who Should Not Have It
Polynucleotide boosters are among the better-tolerated injectables. The usual effects are the injection ones: small bumps for a few hours, redness, occasional pinpoint bruising. They settle without treatment.
TwAc is derived from salmon DNA, so it is not suitable if you have a fish allergy — say so at the consultation. It is also avoided in pregnancy and breastfeeding, with active infection or inflammation in the treatment area, and during an autoimmune flare, which is discussed case by case.
One honest limitation: a booster improves skin, it does not lift it. If what troubles you is sagging rather than surface quality, a thread lift or a biostimulator is the truthful answer, and you will get it.
Who injects it
Dr Azra Vaziri, DHA and DOH licensed, more than twenty years in aesthetic practice and an IMCAS Paris speaker. She injects every patient herself.
Where
Prof Sakla Spanish Eye Clinic on Sheikh Zayed Road in Dubai, and — on Wednesdays — Louvre Medical Clinic in Abu Dhabi. Choose whichever is closer to you.
⎯ Frequently Asked
TwAc FAQ
What does TwAc stand for?
Transdermal Wound Activation Complex. It is an injectable skin booster combining PDRN (polydeoxyribonucleotide, purified from salmon DNA) with hyaluronic acid.
Is TwAc a filler?
No. TwAc adds no volume. It is a bioreparant booster that improves the quality of the skin itself — texture, tone, hydration, fine lines. If you want shape restored, you want filler instead, and the two are often done in separate sessions.
What is the difference between TwAc and Rejuran?
Both are salmon-DNA polynucleotide boosters. Rejuran is PDRN on its own; TwAc pairs PDRN with hyaluronic acid, so hydration and glow come through faster while the repair work happens over the same few weeks. Which suits you depends on how dehydrated your skin is to start with. See Rejuran.
How many TwAc sessions do I need?
Usually three, two to four weeks apart, then maintenance every six to twelve months. A single session gives a signal; a course gives a sustained one. The number is confirmed after your skin is assessed.
How much does TwAc cost in Dubai?
AED 1,300 per session, currently AED 1,100 after discount, at Dr Azra’s clinic. A typical course of three is AED 3,300. Compare across the family on the skin booster price guide.
When will I see results?
Hydration and glow show within a few days, from the hyaluronic acid. The regenerative change — texture, tone, fine lines — builds over four to eight weeks. Judging it in week one tells you very little.
How long do TwAc results last?
Typically six to twelve months after a completed course, depending on your skin, your sun exposure and whether you maintain it. Boosters maintain rather than transform, and they reward being repeated.
Can TwAc be used under the eyes?
Yes — TwAc Eyes is made for that area and treats shadowing, crepiness and fine lines. It does not treat a hollow. If your under-eye problem is loss of volume, that is tear-trough filler, a different treatment.
Is TwAc safe if I am allergic to fish?
No. TwAc is derived from purified salmon DNA, so a fish allergy rules it out. Tell the clinic at the consultation and Dr Azra will plan something else.
Is there any downtime?
Small raised bumps where the product was placed, settling within a few hours and occasionally overnight, plus possible pinpoint bruising. Most patients go straight back to work. Skip the gym and heat for 48 hours and facials for a week.
Can TwAc be combined with other treatments?
Yes. It sits comfortably alongside Botox for dynamic lines and filler for volume, done in separate sessions. It is not usually combined with another booster in the same visit — there is no reason to, and it makes the result impossible to attribute.
Is TWAC the same as the Taiwan Arrival Card?
No — they simply share an acronym. The Taiwan Arrival Card (TWAC) is an immigration document. This page is about TwAc, the injectable PDRN skin booster.
Can I have TwAc in Abu Dhabi?
Yes. Dr Azra treats at Louvre Medical Clinic in Abu Dhabi on Wednesdays and at Prof Sakla Spanish Eye Clinic on Sheikh Zayed Road in Dubai during the week.
Book a Consultation
Dr Azra Vaziri — DHA & DOH licensed aesthetic physician with 20+ years of experience in Dubai & Abu Dhabi.
