PDRN Skin Booster · Dubai & Abu Dhabi

TwAc in Dubai — the PDRN Booster That Comes With Hyaluronic Acid

TwAc is a PDRN skin booster — purified salmon-DNA polynucleotides combined with hyaluronic acid, injected to repair skin quality rather than add volume. Given by Dr Azra Vaziri in Dubai and Abu Dhabi.

PDRN + hyaluronic acid in one booster
Repairs skin quality, adds no volume
Face, under-eyes, neck and hands
AED 1,300, currently AED 1,100

TwAc at a glance
What it is
PDRN booster with HA
TwAc stands for
Transdermal Wound Activation Complex
Source
Purified salmon DNA
Adds volume?
No — it is not a filler
Course
Usually 3 sessions, 2–4 weeks apart
Price
AED 1,300 → AED 1,100

Looking for the Taiwan Arrival Card? That is a different TWAC entirely — this page is about the injectable skin booster.


Quick answer

What is TwAc? TwAc — Transdermal Wound Activation Complex — is an injectable skin booster that combines PDRN (polydeoxyribonucleotide, purified from salmon DNA) with hyaluronic acid. The PDRN signals fibroblasts to repair and rebuild; the hyaluronic acid hydrates at the same time. It treats skin quality — texture, tone, fine lines, dull or tired skin, under-eye shadowing — and adds no volume, so it is not a filler. At Dr Azra Vaziri’s clinic it is AED 1,300, currently AED 1,100, usually as a short course.


If you came here for the wider topic: what PDRN actually is · polynucleotide treatment · Rejuran · skin booster prices


⎯ The Product

What Is TwAc?

TwAc is a bioreparant skin booster: PDRN from purified salmon DNA, formulated together with hyaluronic acid. It is injected into the skin to repair quality, not underneath it to create shape.

PDRN — polydeoxyribonucleotide — is made of short, purified DNA fragments. Injected into the dermis it activates fibroblasts, improves microcirculation and damps inflammation, so the skin behaves more like younger skin rather than being padded out to look like it.

What separates TwAc from a pure PDRN product is the second ingredient. Rejuran, the best-known salmon-DNA booster, is PDRN on its own: the repair signal without a hydrating carrier. TwAc pairs the same class of molecule with hyaluronic acid, so hydration and glow arrive within days while the regenerative work happens quietly over the following weeks.

It is sold as a small family — TwAc Eyes for the under-eye area, TwAc 2.0 for early ageing and hydration, and TwAc 3.0 for more mature skin, the neck and the hands. Which one suits you is decided at the consultation, not ordered from a menu.

TwAc is not a filler and it is not Botox. It will not restore a flattened cheek or sharpen a jawline — for that you want filler or a biostimulator. TwAc changes how the skin itself looks and behaves. The two jobs are often done together, in different sessions.

TwAc — Key Facts at a Glance
Full name
Transdermal Wound Activation Complex
Active
PDRN / polynucleotides from purified salmon DNA
Second ingredient
Hyaluronic acid
Treatment type
Injectable bioreparant skin booster
Adds volume?
No — not a filler
First changes
Hydration and glow within days
Full effect
Builds over 4–8 weeks
Typical course
3 sessions, 2–4 weeks apart
Maintenance
Every 6–12 months
Areas
Face, under-eyes, neck, décolletage, hands
Downtime
Small bumps for a few hours; back to normal same day
Price
AED 1,300 per session (currently AED 1,100)
How many sessions your skin needs is decided after an assessment — book a consultation.

⎯ How It Works

Repair, Not Fill

A filler occupies space. A booster changes the tissue. TwAc is firmly in the second category, and the mechanism is worth understanding because it explains why nothing dramatic happens on the day and why the result keeps improving after you have stopped thinking about it.

The PDRN fragments act as signalling molecules: they bind receptors on fibroblasts and switch them toward repair — new collagen and elastin, better microcirculation, less oxidative stress. The hyaluronic acid does something simpler and faster: it holds water, so the skin looks plumper and brighter within days while the slower work is still under way.

That split is also why TwAc is given as a course rather than a single session. One injection gives a signal; three, spaced two to four weeks apart, give a sustained one.


⎯ Where It Is Used

TwAc Treatment Areas

Anywhere the complaint is skin quality rather than shape.

Area What it is used for Which formulation
Face Dull, tired skin, uneven texture, fine lines, early laxity TwAc 2.0 or 3.0
Under-eyes Shadowing, crepiness and fine lines — not hollowing TwAc Eyes
Neck Crepey texture and horizontal lines TwAc 3.0
Décolletage Sun damage, texture, fine crinkling TwAc 3.0
Hands Thin, crepey skin on the back of the hand TwAc 3.0

The formulation is chosen at the consultation. Under-eye HOLLOWING is a volume problem and needs a different treatment — see tear-trough filler.


⎯ Where TwAc Sits

TwAc, Rejuran, Polynucleotides and Profhilo

These overlap, and the honest answer is that the differences between them matter less than whether a booster is the right category for you at all. Dr Azra picks on your skin, not on the brand.

TwAc Rejuran Polynucleotides (generic) Profhilo
Active PDRN + hyaluronic acid PDRN (salmon DNA) PN / PDRN, various brands High-concentration HA
Main job Repair + hydration Repair Repair Hydration and bio-remodelling
Adds volume No No No No
Typical course 3 sessions 3–4 sessions 3 sessions 2 sessions
Price / session AED 1,100 AED 1,500 from AED 1,100 AED 1,300

Prices are the current after-discount rates from Dr Azra’s list and are “from” figures; the plan is confirmed in clinic.


⎯ The Session

What the Appointment Is Like

Numbing cream first, then a series of small injections across the treatment area. It takes twenty to thirty minutes. You will have small raised bumps where the product was placed — these settle within a few hours, occasionally overnight.

Most people go straight back to work. Leave make-up off for the rest of the day, skip the gym and anything hot for forty-eight hours, and no facials or actives for a week. The full care guidance is on the salmon DNA aftercare page, which covers PDRN boosters as a family.


⎯ Cost

TwAc Price in Dubai

TwAc at Dr Azra’s clinic is AED 1,300 per session, currently AED 1,100 after discount. Boosters work as a course, so the figure worth planning around is three sessions — and whether you need three is decided after your skin is assessed, not before.

Per session Typical course of 3
TwAc AED 1,100 AED 3,300

From Dr Azra’s current clinic list. Sessions are spaced two to four weeks apart. See the full clinic price list or the skin booster price guide to compare across the family.


⎯ Safety

Side Effects and Who Should Not Have It

Polynucleotide boosters are among the better-tolerated injectables. The usual effects are the injection ones: small bumps for a few hours, redness, occasional pinpoint bruising. They settle without treatment.

TwAc is derived from salmon DNA, so it is not suitable if you have a fish allergy — say so at the consultation. It is also avoided in pregnancy and breastfeeding, with active infection or inflammation in the treatment area, and during an autoimmune flare, which is discussed case by case.

One honest limitation: a booster improves skin, it does not lift it. If what troubles you is sagging rather than surface quality, a thread lift or a biostimulator is the truthful answer, and you will get it.


⎯ Frequently Asked

TwAc FAQ

Transdermal Wound Activation Complex. It is an injectable skin booster combining PDRN (polydeoxyribonucleotide, purified from salmon DNA) with hyaluronic acid.

No. TwAc adds no volume. It is a bioreparant booster that improves the quality of the skin itself — texture, tone, hydration, fine lines. If you want shape restored, you want filler instead, and the two are often done in separate sessions.

Both are salmon-DNA polynucleotide boosters. Rejuran is PDRN on its own; TwAc pairs PDRN with hyaluronic acid, so hydration and glow come through faster while the repair work happens over the same few weeks. Which suits you depends on how dehydrated your skin is to start with. See Rejuran.

Usually three, two to four weeks apart, then maintenance every six to twelve months. A single session gives a signal; a course gives a sustained one. The number is confirmed after your skin is assessed.

AED 1,300 per session, currently AED 1,100 after discount, at Dr Azra’s clinic. A typical course of three is AED 3,300. Compare across the family on the skin booster price guide.

Hydration and glow show within a few days, from the hyaluronic acid. The regenerative change — texture, tone, fine lines — builds over four to eight weeks. Judging it in week one tells you very little.

Typically six to twelve months after a completed course, depending on your skin, your sun exposure and whether you maintain it. Boosters maintain rather than transform, and they reward being repeated.

Yes — TwAc Eyes is made for that area and treats shadowing, crepiness and fine lines. It does not treat a hollow. If your under-eye problem is loss of volume, that is tear-trough filler, a different treatment.

No. TwAc is derived from purified salmon DNA, so a fish allergy rules it out. Tell the clinic at the consultation and Dr Azra will plan something else.

Small raised bumps where the product was placed, settling within a few hours and occasionally overnight, plus possible pinpoint bruising. Most patients go straight back to work. Skip the gym and heat for 48 hours and facials for a week.

Yes. It sits comfortably alongside Botox for dynamic lines and filler for volume, done in separate sessions. It is not usually combined with another booster in the same visit — there is no reason to, and it makes the result impossible to attribute.

No — they simply share an acronym. The Taiwan Arrival Card (TWAC) is an immigration document. This page is about TwAc, the injectable PDRN skin booster.

Yes. Dr Azra treats at Louvre Medical Clinic in Abu Dhabi on Wednesdays and at Prof Sakla Spanish Eye Clinic on Sheikh Zayed Road in Dubai during the week.


⎯ The Rest of the Family

Related Treatments

TwAc is one product in a family we treat with every week. These pages explain the rest.

Book a Consultation

Dr Azra Vaziri — DHA & DOH licensed aesthetic physician with 20+ years of experience, practising in Dubai and Abu Dhabi.