Regenerative Aesthetics · Rejuran · Dubai
Rejuran Dubai — Salmon DNA (PDRN) Skin Booster
Rejuran — also known as Rejuran Healer or the “baby salmon injection” — is a PDRN-based injectable treatment originally developed in South Korea. PDRN (polydeoxyribonucleotide) is a bioactive molecule extracted from salmon DNA that activates your skin’s own repair mechanisms at a cellular level.
- 30–45 minutesProcedure Time
- Bumps 24–48 hoursRecovery
- 3–4 recommendedSessions
- Build over 4–6 weeksResults
Rejuran Dubai — Salmon DNA (PDRN) Skin Booster at a glance
Rejuran in Dubai with Dr Azra Vaziri — salmon DNA (PDRN) skin booster injections for skin repair, texture, acne scars and under-eyes. At Dr Azra's Dubai clinic.
- Procedure Time
- 30–45 minutes
- Recovery
- Bumps 24–48 hours
- Sessions
- 3–4 recommended
- Results
- Build over 4–6 weeks
From AED 1,500 · Performed by Dr Azra Vaziri at Prof Sakla Spanish Eye Clinic, Dubai
Where Rejuran Is Available
What Is Rejuran
Quick Answer — What Is Rejuran?
The Rejuran skin booster is a regenerative salmon-DNA injectable — a skin healer rather than a filler.
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It works by injecting PDRN (salmon DNA fragments) into the skin to activate cellular repair, reduce inflammation, and stimulate collagen from within. It treats dull skin, fine lines, scars, enlarged pores, and dark circles. Treatment takes 30–45 minutes, requires 3–4 sessions, and results build progressively over weeks.
Why salmon? Salmon DNA shares over 90 percent structural similarity with human DNA, making it exceptionally biocompatible. The extracted PDRN undergoes rigorous pharmaceutical-grade purification to remove all proteins, lipids, and potential allergens, leaving only the therapeutic nucleotide sequences. This is not a cosmetic topical — it is a clinically proven regenerative injectable that works by activating your body’s own repair mechanisms.
Understanding the terminology: salmon DNA is the biological source. PDRN (polydeoxyribonucleotide) refers to the shorter, purified DNA fragments used therapeutically. Polynucleotides (PN) — and TwAc, which pairs PDRN with hyaluronic acid are longer DNA chains with broader collagen-stimulating properties. In practice, these terms are often used interchangeably — all are derived from the same salmon DNA source and share the same regenerative mechanism, and Rejuran is the most recognised brand built on it.
The treatment originated in South Korea’s regenerative medicine laboratories, where researchers studying wound healing discovered that purified salmon DNA fragments could dramatically accelerate tissue repair. Rejuran pioneered the injectable format, and salmon DNA treatment has since become one of the most popular regenerative skin therapies across Asia, Europe, and now the Middle East.
Unlike skin boosters that hydrate or Profhilo that bio-remodels, Rejuran works through the DNA salvage pathway — providing nucleotides that damaged cells need to repair themselves. It also binds to adenosine A2A receptors, producing a powerful anti-inflammatory effect. The result is skin that heals itself from within rather than being temporarily plumped or filled.
Rejuran sits within Dr Azra’s broader polynucleotide and regenerative aesthetics offering. For a detailed comparison with other regenerative treatments, read what are polynucleotides and our salmon DNA facial guide.
What Rejuran Treats
- Dull, dehydrated, tired-looking skin
- Fine lines and early wrinkles
- Acne scarring and enlarged pores
- Dark circles and under-eye hollowing
- Uneven skin tone and texture
Treatment Highlights
Not sure whether Rejuran is the right answer for your skin concern? Book a consultation with Dr Azra and she will assess your skin in person.
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- Biologically active — repairs at cellular level
- Anti-inflammatory (adenosine A2A pathway)
- 30–45 minute procedure
- Minimal downtime — bumps resolve in 24–48 hours
- Results build progressively over 4–6 weeks
Rejuran Product Range — Healer, I (Eye) and HB
Rejuran comes in several formulations, each designed for specific skin concerns and treatment areas.
Rejuran Healer
Most PopularThe original PDRN skin healer. Targets overall skin quality — texture, tone, hydration, and fine lines. Best for full-face rejuvenation and general skin repair. The foundation of most Rejuran protocols.
Rejuran I (Eye)
Under-Eye SpecialistSpecifically formulated for the delicate periorbital area. Treats dark circles, under-eye crepiness, and fine lines around the eyes. Lower viscosity for safe use in thin-skinned areas.
Rejuran HB
Hydration BoostCombines PDRN with hyaluronic acid for patients who need both biological repair and immediate hydration. Best for severely dehydrated skin that needs structural healing alongside moisture restoration.
Other Polynucleotide Brands
Rejuran is the original Korean salmon-DNA PDRN injectable and the most recognised name, but Dr Azra also works with other registered polynucleotide products where they fit a patient better — Nucleofill and Plinest from Italy, and Ameela and PhilArt from the UK and Europe. Which product suits you is a clinical decision made at consultation. For the full landscape, see the polynucleotide treatment guide.
Which Rejuran formulation suits you is decided in person, not from a photograph — ask Dr Azra which Rejuran is right for your skin.
Rejuran Injections by Treatment Area
Rejuran salmon DNA injections are not delivered as one blanket treatment. Dr Azra places a grid of shallow micro-injections so the PDRN sits in the layer that needs repairing, and the area being treated decides which Rejuran formulation she selects and how the protocol is spaced. Below is how Rejuran injection treatment is planned in Dubai for the four concerns patients ask about most.
Full Face — Skin Quality
Rejuran HealerThe standard Rejuran injection protocol: micro-boluses across the cheeks, forehead, temples and jawline to rebuild overall skin quality.
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This is the option chosen for dull, tired, heat-stressed skin and early fine lines, and it is the version most people mean when they search for Rejuran in Dubai or salmon DNA in Dubai. Usually 3–4 sessions, 2–4 weeks apart.
Rejuran I · PDRN Under Eyes
Under-Eye — Dark Circles and Crepiness
PDRN under the eyes is one of the most requested Rejuran treatments.
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The periorbital skin is thin, so Dr Azra uses the lower-viscosity Rejuran I formulation and very superficial placement to soften dark circles, crepey texture and fine lines without adding volume. It repairs skin quality rather than filling a hollow.
Acne Scars and Enlarged Pores
Rejuran HealerFor post-acne marks, rolling scars and open pores, Rejuran injections are targeted into the scarred zones, often combined with Dermapen microneedling so the PDRN reaches the remodelling layer.
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Results are gradual: the skin rebuilds collagen over several weeks rather than resurfacing in one session. See acne scar treatment.
Dry, Dehydrated and Heat-Stressed Skin
Rejuran HBDubai air conditioning and summer heat leave skin dehydrated as well as damaged.
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Rejuran HB pairs PDRN with hyaluronic acid so a single injection session delivers both cellular repair and immediate water-binding hydration. It is the formulation Dr Azra reaches for when skin needs structural healing and moisture at the same time.
Neck, Décolletage, Hands & Scalp
Beyond the FaceBecause salmon DNA works at a cellular level rather than adding volume, it can be used safely in areas that are difficult to treat with fillers: horizontal neck lines and crepey texture, sun damage on the décolletage, crepey skin and visible veins on the hands, and the scalp
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— where PDRN stimulates hair follicle activity alongside hair restoration treatments or PRP therapy.
Treating more than one of these areas in the same course is common. Tell Dr Azra what is bothering you and she will map the injection plan around it.
Is Rejuran the Same as PDRN Therapy and Polynucleotides in Dubai?
Short answer: yes and no. Rejuran is a PDRN treatment, and PDRN is a type of polynucleotide — but the three words are not interchangeable. Salmon DNA is the raw material. PDRN is what that DNA is processed into. Polynucleotide is the chemical family PDRN belongs to. Rejuran is one specific Korean branded product made from it. So every Rejuran session is a PDRN treatment, but not every PDRN or polynucleotide offer in Dubai is Rejuran.
Why it matters when you are comparing quotes: a clinic can advertise “PDRN” or “polynucleotide therapy” honestly while using a product that is not Rejuran, and the prices are not the same. Ask which product is being used, and ask to see the carton before it is opened. Dr Azra uses other registered polynucleotide products where they genuinely fit — but they are named at the consultation, not substituted quietly. The science shared by all of them is explained in what PDRN is, and current Rejuran pricing in Dubai is listed separately.
| Term | What it actually refers to | Where you see it |
|---|---|---|
| Salmon DNA | The biological source — purified DNA extracted from salmon, over 90% structurally similar to human DNA. | Consumer and social-media name for the treatment |
| PDRN | Polydeoxyribonucleotide — the shorter, pharmaceutical-grade DNA fragments that are actually injected. This is the active ingredient. | Clinical and product literature |
| Polynucleotide | The wider chemical family PDRN sits in. Several registered brands besides Rejuran are polynucleotide products. | The polynucleotide treatment category |
| Rejuran | One specific branded PDRN product from South Korea — the original, and the most recognised name. | This page |
Price confirmed after selecting the product and treatment plan at consultation.
How Salmon DNA (PDRN) Repairs Your Skin
When purified PDRN fragments are injected into the dermis, they bind to adenosine A2A receptors on skin cells. This activates a cascade of biological responses that fundamentally differ from hyaluronic acid treatments or dermal fillers. Rather than hydrating or adding volume, PDRN tells your cells to repair, rebuild, and regenerate.
The treatment stimulates fibroblast proliferation — the cells responsible for producing collagen and elastin. It upregulates vascular endothelial growth factor (VEGF) production, promoting the formation of new blood vessels that improve nutrient delivery and oxygenation to the skin. It also reduces matrix metalloproteinases (MMPs), the enzymes that break down existing collagen. The net result is both new collagen construction and protection of existing structural proteins.
This dual action — building new and preserving old — is what makes salmon DNA therapy uniquely powerful for patients seeking genuine skin regeneration rather than cosmetic masking. The effects develop progressively over weeks as your biology responds, with visible improvements continuing for months after each session.
How Rejuran Treatment Works
Consultation
Skin assessment, concern discussion, and Rejuran product selection with Dr Azra — book a consultation.
Numbing
Topical anaesthetic cream applied for 20 minutes to ensure comfort during injection.
PDRN Injection
Micro-injections of Rejuran across the treatment area. 30–45 minutes. Can be delivered via needle or Dermapen.
Heal & Repair
Small bumps resolve 24–48 hours. PDRN activates repair over 4–6 weeks. Repeat every 2–4 weeks.
Rejuran vs Other Skin Treatments
| Treatment | Mechanism | Best For | Sessions |
|---|---|---|---|
| Rejuran (PDRN) | DNA repair + anti-inflammation | Skin repair, scars, dark circles | 3–4 |
| Profhilo | HA bio-remodelling | Skin laxity, hydration, fine lines | 2 |
| Skin Boosters | HA micro-injection hydration | Dehydration, glow, superficial lines | 3 |
| Exosomes | Cell-derived signalling vesicles | Deep regeneration, post-procedure | 3–4 |
| PRP | Autologous growth factors | Natural regeneration, hair, healing | 3–4 |
Salmon DNA vs Profhilo
Salmon DNA (PDRN) and Profhilo are both regenerative treatments, but they work through entirely different mechanisms.
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PDRN activates the adenosine A2A receptor pathway for deep cellular repair, collagen stimulation, and anti-inflammatory action — making it particularly effective for dark circles, scarring, and barrier-damaged skin. Profhilo uses high-concentration hyaluronic acid for broad bio-remodelling, hydration, and an immediate glow. Dr Azra often combines both in layered protocols — PDRN for deep cellular repair, Profhilo for surface hydration and radiance.
Salmon DNA vs Exosome Therapy
Both are regenerative, but they deliver different biological signals. PDRN provides nucleotide building blocks and activates specific A2A receptors for collagen production and tissue repair.
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Exosome therapy delivers growth factors, peptides, and genetic material via nano-vesicles for broader cellular signalling. Exosomes are particularly effective post-procedure (after microneedling or laser), while PDRN excels as a standalone regenerative treatment. They can be combined for multi-pathway cellular regeneration.
PDRN vs PRP
PRP (platelet-rich plasma) uses your own blood platelets and growth factors — it is autologous, carrying virtually zero allergy risk.
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PDRN uses purified salmon DNA fragments that work through the adenosine receptor pathway. Both stimulate collagen and tissue repair but through different mechanisms. PRP has a longer clinical track record in aesthetics; PDRN offers stronger anti-inflammatory and barrier-repair properties. They can be combined in the same treatment course for enhanced results.
See also: Profhilo vs Rejuran · Profhilo vs polynucleotides · PRP vs exosomes
Who Plans Your Rejuran Course — Dr Azra Vaziri
Salmon-DNA is a course, not a single appointment, and most of the outcome is decided by depth, spacing and how many sessions are actually needed rather than by the vial.
Every Rejuran Dubai — Salmon DNA (PDRN) Skin Booster appointment at this clinic is assessed and injected by Dr Azra Vaziri herself — a DHA- and DOH-licensed aesthetic physician with more than 20 years of experience, practising aesthetic medicine since 2004.
Training behind the protocol
- Mesotherapy workshops — Mesoestetic Pharma Group distributor in Iran (2018–2023) — Rejuran is delivered by multi-point micro-injection, the technique these workshops are built on.
- Aliaxin and Profhilo injection workshop — IBSA distributor in Iran (2018–2023) — she ran the injection workshops for IBSA, whose Profhilo is the treatment Rejuran is most often weighed against on this page.
- Speaker — IMCAS World Congress 2024 (Paris), and Dubai Derma in 2023 and 2026
Who Is a Good Candidate for Rejuran
Ideal Candidates
- Dull, tired-looking skin needing repair
- Fine lines and early signs of ageing
- Acne scarring or post-inflammatory marks
- Dark circles and under-eye ageing
- Sun-damaged or heat-stressed skin (common in Dubai)
- Patients wanting biological repair, not just hydration
Considerations
A consultation with Dr Azra determines suitability and selects the right Rejuran formulation.
- Allergy to fish or salmon products
- Pregnancy or breastfeeding
- Active skin infection in treatment area
- Keloid scarring tendency
- Autoimmune conditions (discuss with Dr Azra)
Rejuran Care Guidelines
Before Treatment
- Avoid blood thinners for 1 week
- Avoid alcohol for 48 hours
- Inform Dr Azra of any fish allergies
- Stay hydrated
- Arrive with clean skin — no makeup
After Treatment
If anything after your Rejuran session worries you, contact the clinic rather than waiting for your next appointment.
- Small bumps at injection sites — resolve in 24–48 hours
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- No makeup for 12 hours
- Avoid sun exposure and heat for 48 hours
- No active skincare (retinol, AHA) for 48 hours
- Use gentle cleanser and SPF from day 2
- Results build over 4–6 weeks per session
Before & After Care
Preparing for or recovering from a session? The full salmon DNA / PDRN before & after care guide
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— do’s, don’ts and a day-by-day recovery timeline — applies to Rejuran and other salmon-DNA / PDRN treatments.
Frequently Asked Questions
What is Rejuran?
Rejuran is a PDRN-based injectable skin healer derived from salmon DNA. It activates cellular repair pathways, stimulates collagen and elastin production, reduces inflammation, and improves skin hydration, elasticity, and texture. It is one of the most popular regenerative skin treatments globally and is now widely available in Dubai.
How is Rejuran different from Profhilo?
Profhilo is a hyaluronic acid bio-remodeller that hydrates and tightens skin. Rejuran is a PDRN that repairs skin at the DNA level. Profhilo works from the outside in (hydration → collagen). Rejuran works from the inside out (cellular repair → regeneration). They complement each other and can be combined. Read our Profhilo vs Rejuran comparison.
How is Rejuran different from other polynucleotides?
Rejuran is a branded PDRN product — a specific type of polynucleotide. All PDRN is polynucleotide-based, but not all polynucleotide products are Rejuran. Rejuran Healer uses a specific molecular weight and concentration optimised for skin repair. Other brands include Plinest, Nucleofill, and Mastelli.
How many Rejuran sessions do I need?
Most patients need 3–4 sessions spaced 2–4 weeks apart. Improvement is progressive — skin quality continues to improve for several weeks after each session. Maintenance sessions every 3–6 months sustain results.
Is Rejuran the same as salmon DNA treatment?
Rejuran is derived from salmon DNA — specifically the PDRN extracted from salmon. “Salmon DNA treatment” is a general term encompassing Rejuran and similar PDRN products. Rejuran Healer is the most recognised branded version. See our salmon DNA facial guide.
What is the downtime after Rejuran?
Small raised bumps at injection sites are normal and resolve within 24–48 hours. Mild redness may last a day. Most patients return to normal activities immediately. Avoid makeup for 12 hours, sun exposure for 48 hours, and active skincare for 2–3 days.
Can Rejuran be combined with other treatments?
Yes. Dr Azra commonly combines Rejuran with Profhilo for hydration + repair, Dermapen microneedling for enhanced penetration, or skin boosters for combined hydration and biological repair. The best combination is determined during consultation.
Can I buy Rejuran in Dubai?
Rejuran is a prescription medical injectable, not a retail product. In the UAE it can only be supplied and administered by a licensed doctor inside a licensed clinic, so there is no legitimate way to buy Rejuran in Dubai for use at home — anything sold that way is not the medical product. Dr Azra administers Rejuran in person after a consultation that confirms the right formulation for your skin.
Is Rejuran available in Abu Dhabi?
Yes. Dr Azra Vaziri sees patients at two clinics: Prof Sakla Spanish Eye Clinic on Sheikh Zayed Road, Dubai, and — on Wednesdays — Louvre Medical Clinic in Abu Dhabi. Choose whichever is closer to you. The Rejuran protocol, the formulations used and the aftercare are unchanged — call +971 50 180 1793 to arrange a consultation.
Does Rejuran treatment hurt?
Most patients find it very comfortable. Topical numbing cream is applied before the procedure. Ultra-fine needles are used. Most patients describe mild prickling. The procedure takes 30–45 minutes.
When will I see results from Rejuran?
Improved hydration and a subtle glow within the first week. Significant improvements in texture, elasticity, and fine lines over 4 to 6 weeks as collagen remodelling occurs. Results compound with each session.
How long do Rejuran results last?
6 to 12 months from a full course, depending on skin condition, lifestyle, and environment. Regular maintenance every 3 to 6 months sustains and builds upon improvements.
Can Rejuran help with dark circles?
Yes. PDRN is particularly effective for the under-eye area — improving microcirculation through angiogenesis, thickening thin skin via collagen stimulation, and reducing pigmentation. Dr Azra will assess whether PDRN alone or combined with under-eye filler is most appropriate.
Is Rejuran safe?
Yes. Rigorously purified to remove all proteins and allergens. Over 90% structural similarity with human DNA ensures excellent biocompatibility. Side effects are mild — redness and swelling resolving within 24 to 48 hours. Not recommended for patients with fish allergies.
What is the price of Rejuran in Dubai?
Rejuran is AED 1,500 per session (standard AED 1,700). Package pricing is confirmed at consultation.
What is the difference between Rejuran, Nucleofill, and Plinest?
All three are polynucleotide injectables that stimulate collagen and repair skin, but they differ in formulation and origin. Rejuran (South Korea) uses highly purified salmon PDRN — the original that started the global trend. Available as Rejuran Healer for face, Rejuran I for under-eyes, and Rejuran S for scars. Nucleofill (Italy) uses high-molecular-weight polynucleotides with patented HPT purification, CE-marked. Plinest (Italy) is derived from trout DNA with variants for face, eye, and body. Dr Azra selects the most appropriate brand based on your treatment area and goals.
Can men get Rejuran treatment?
Yes. Suitable for both men and women. Increasingly popular among men in Dubai seeking improved skin quality without visible structural change.
Book a Consultation
Dr Azra Vaziri — DHA & DOH licensed aesthetic physician with 20+ years of experience in Dubai & Abu Dhabi.
