Unlike cosmetic Botox that targets muscles, hyperhidrosis treatment targets the eccrine sweat glands. Botulinum toxin blocks the release of acetylcholine — the neurotransmitter that activates sweat production — reducing sweating by 80 to 90 percent in the treated area. The effect is longer-lasting than cosmetic Botox — typically 6 to 9 months — because sweat glands respond differently than muscles.

Dubai’s hot, humid climate makes this treatment particularly valuable. Patients who have lived with excessive underarm sweating, wet palms during meetings, or visible forehead perspiration report dramatic quality-of-life improvement after treatment. Many describe it as one of the most impactful procedures they have ever had.

Dr Azra Vaziri selects the right neuromodulator brand (Botox, Dysport, or Xeomin) based on the treatment area, severity of sweating, and patient preference. The number of units required is higher than cosmetic areas — typically 50 per underarm (100 total) — reflecting the broader treatment zone.

• Target: Eccrine sweat glands
• Units: 50–100 per area (full dosage guide)
• Products: Botox, Dysport, or Xeomin
• Price: AED 2,000 – 3,500
• Duration: 6–9 months
• Onset: 3–7 days

• Underarms — most common, strongest evidence
• Palms — effective but more sensitive
• Forehead — for visible perspiration
• Feet — plantar hyperhidrosis
• Can combine with cosmetic Botox in same session

Dubai’s climate creates unique challenges for patients with hyperhidrosis. Temperatures exceeding 45°C in summer, high humidity, and the social expectation of well-groomed presentation make excessive sweating more than a medical inconvenience — it affects confidence, clothing choices, professional interactions, and daily comfort.

Antiperspirants and oral medications address symptoms partially but often fail for moderate to severe cases. Botox treats the underlying mechanism — blocking sweat gland activation at the source — delivering 80 to 90 percent sweat reduction that lasts through the summer months and beyond.

Many patients schedule their treatment in spring (March to May) so they are fully dry before peak summer heat. A single session provides 6 to 9 months of relief — covering the entire hot season. See our body treatments page for other treatments in this category.

Before treatment — Dr Azra assesses the severity and distribution of your sweating. An iodine-starch test may be used to map the most active sweat zones — a yellow-brown solution is applied to the skin and dusted with starch, which turns dark blue-black where sweating is heaviest. This ensures injections are placed precisely where they are needed most. Shave underarms 24 hours before if treating the axillae. Avoid antiperspirant on treatment day.

During treatment — Topical anaesthetic or ice is applied. Dr Azra administers multiple micro-injections in a grid pattern across the treatment area using a fine needle. Underarm treatment takes approximately 15 to 20 minutes per side. Palm treatment may take slightly longer and can be more sensitive due to nerve density in the hands.

After treatment — You can return to normal activities the same day. Avoid intense exercise, saunas, and hot baths for 24 hours. Do not apply antiperspirant for 24 hours. Results develop over 3 to 7 days as the acetylcholine blockade takes effect. Full dryness is typically achieved by two weeks.

Results timeline — Sweat reduction of 80 to 90 percent lasts 6 to 9 months. Some patients experience even longer duration — up to 12 months. Treatment is repeated as sweating gradually returns. Many patients notice that with repeated treatments, the duration extends and the severity of sweating decreases even between sessions.

Hyperhidrosis Botox has minimal downtime. Follow these guidelines:

• Do not apply antiperspirant or deodorant
• Avoid intense exercise, saunas, hot baths
• Wear loose, breathable clothing
• Do not rub or massage the treated area
• Minor bruising at injection sites is normal

• Resume normal antiperspirant use after 24 hours
• Dryness increases progressively day by day
• Full effect reached by day 10–14
• Contact the clinic if sweating does not reduce
• A review can be scheduled at 2 weeks

For detailed post-treatment guidance covering all Botox areas, see our complete Botox aftercare guide.

• Excessive underarm sweating that soaks through clothing
• Wet palms affecting handshakes and daily activities
• Visible forehead perspiration in social or professional settings
• Sweating that occurs regardless of temperature or activity
• Antiperspirants and oral medications have been inadequate
• Patients wanting to stay dry during Dubai’s summer months

• Pregnancy or breastfeeding
• Allergy to botulinum toxin or albumin
• Neuromuscular disorders (e.g. myasthenia gravis)
• Active skin infection in the treatment area
• Secondary hyperhidrosis caused by medication or medical condition (requires investigation first)

Suitability is confirmed during your consultation with Dr Azra.

Hyperhidrosis Botox with Dr Azra Vaziri starts from AED 2,000 for underarm treatment. Final pricing depends on the area treated, the number of units required, and the product used. Underarms typically require 100 units total (50 per side). Palms and larger areas may require higher unit counts.

While hyperhidrosis Botox costs more per session than cosmetic Botox due to the higher unit count, the results also last significantly longer — 6 to 9 months versus 3 to 4 months — making the cost per month of dryness comparable or even lower than many cosmetic treatments.

For a detailed breakdown of units and costs by treatment area, see our How Many Units of Botox guide and our Botox pricing page.